ALRI Restore 90c





ALRI Restore 90c
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Retail Price: $70.99
Your Price: $36.89





Restore 90 caps

In the ever expanding world of performance and health supplementation today, there is an assumed division between products considered "hard-core only", and those that are intended to promote lean mass acquisition by way of improved over-all health. Both groups of users actually may have the same goals especially men.

Facts:

  1. We are performance oriented men and want as much muscle building, sex-driving testosterone as humanly possible. I mean come on, can you find a guy that says 'I want to be fat and feminine' (okay, one that isn't looking for a sex-change). We all want to be healthy optimized males!
  2. We don't want to deal with the negative side affects of excess estrogen from any source. It shuts down testosterone production and makes people fat and bitchy. We like being men!
  3. We don't want or need prolactin increases to kill our libido, give us gyno, or make us want to have a "nesting" moment.
  4. If we did want excess estrogen and prolactin, we would be eating soy-everything and watching day-time drama shows instead of watching UFC.
  5. We hate working our asses off to build lean mass only to have cortisol production soar from all of training and life's everyday stresses resulting in muscle loss and fat deposits around the waist. We worked for the muscle and we want to keep it.

Estrogens, Prolactin and Cortisol Oh My!

In today's "soy-everything/estrogen is good/testosterone is evil" world, men have to deal with countless phyto and xeno-estrogens in our foods and environment. Naturally it only gets worse when we realize that these feminizing phyto and xeno-estrogens are ADDED to our own natural estrogen production in our bodies. Not bad enough? Okay, then some of us also add products that aromatize to estrogens.

Yeah, still worse

Each of these feminizing factors cause a net and additive negative affect upon our lean mass and other things male and they add up. The results are 3 fold:

  1. Additional fat that produces additional aromatase enzyme resulting in even more of our manly testosterone being converted into un-manly estrogens. As most are now aware, aromatase enzyme converts testosterone and other androgens into estrogens.

  2. The increase in estrogens suppresses our male testosterone production system via inhibition of the the HPTA.

  3. Excess estrogen production causes another feminizing hormone to kick in

Prolactin is a single-chain protein hormone that has serious feminizing actions (like lactation, increased breast size, HPTA inhibition and suppression of GH production). There are a few reasons prolactin levels increase, but the one that is most common and preventable is that when estrogen levels elevate so do prolactin levels in males and females alike.

Many are already aware that the first key to optimized testosterone production is getting rid of excess estrogen in males while stimulating LH production, and some are even aware that getting prolactin to go away once it starts is not always simply a matter of getting rid of the estrogen problems. But most are unaware of how all of this correlates and is compounded by the hormone group that triggers serious lean tissue loss.

Glucocorticoids are a group of steroids that originate at the adrenal cortex of the adrenal glands (above your kidneys). The most commonly discussed hormone of this group is cortisol. When a cortisol molecule meets up with a muscle cell, it triggers the release of amino acids from the cell. That probably does not sound like a big deal until you realize that these amino acids come from the breaking down of the muscle cell proteins. This of course means all of that hard earned lean mass tissue begins to waste away and become energy or toilet trash.

Cortisol levels are elevated as a result of stress. Unfortunately, the body views stress stimuli such as increases in muscle tissue mass, training, sickness, and the spouse in a bad mood as reason to increase circulatory cortisol levels. Cortisol production can also inhibit endogenous GH and testosterone production while fueling pathways that allow additional aromatase enzyme producing fat to accumulate around the waist and upper legs.

So, increases in cortisol production means less muscle, more fat, and aromatization >estrogen->prolactin

and less testosterone production to counter it with. Kind of sucks, huh?

Time to Restore

ALR Industries Restore is not just another testosterone booster. Though an increase in testosterone production alone is pretty cool, and one of the reported major benefits of Restore, it would be only part of the Restore optimized male matrix. Instead we have opted to see how many arguments we can start (and knock-offs we can inspire) this time by raising the bar for product expectations beyond what any one product can currently offer performance oriented males by doing the whole job. Its okay, we are men, we like competition!

Estrogen Control

6-Bromodione: There are two types of estrogen aromatase inhibitors and application of only one leaves the other pathway open for feminizing potential.

  1. 6 alpha-Bromodione is a competitive inhibitor of aromatase enzymes. Basically this means it works by way of binding to the active binding site of the aromatase enzyme resulting in prevention of interaction with other steroids that aromatize like testosterone and the rest of our favorite male androgens. This is great for rapid binding and short term aromatase control, but unfortunately a competitive inhibitor will eventually let go of the enzyme and allow it to do feminizing things to manly hormones. So, only half of the job is done, but it has its important role as well.
  2. 6 beta-Bromodione is a mechanism-based irreversible inhibitor of the aromatase enzyme. An irreversible aromatase inhibitor is also referred to as a suicide inhibitor. It's pretty cool in that it acts similar to a competitive inhibitor in the way it binds, but like a pissed-off ex-girlfriend, it is both highly selective and it will not let go until death do they part.

Together the two analogs in 6-Bromodione make sure that estrogen is under control, and many would assume that less estrogen means the prolactin would be under control as well. Often, once prolactin increases are stimulated, shutting it back down takes some extra effort and a protracted period of time. How long are you willing to wait to be an optimized male?

Prolactin Inhibition

Many have heard of or used drugs like bromocriptine that inhibit prolactin production for medical needs. Of course one of the benefits is an often reported increase in libido, and related factors, but the side-effects such as nausea and dry mouth can certainly negate the positive.

Prolact-X (Chasteberry Diterpine Matrix Extract)
There has been a long history of supplemental use of Chasteberry for treatment of PMS in women. Most researches believe that PMS is commonly the result of high prolactin levels so no surprise that we took an interest in this herb.

The amino acid dopamine is the body's natural controller of prolactin release. Of course many dopaminergic compounds have been noted as effective treatments for increasing GH secretion as well, which correlates rather well with optimization in male performance due to the fact that elevated prolactin results in decreased GH and IGF-1 production.

The search for the prolactin-suppressive principles in Chasteberry provided a number of compounds with dopaminergic properties. In short, research showed that they bound to recombinant dopamine DA2-receptors and suppressed prolactin release from cultivated lactotrophs as well as in animal experiments. The search for the chemical identity of the dopaminergic compounds resulted in isolation of a number of diterpenes of which some clerodadienols were most important for the prolactin-suppressive effects. They were almost more effective in their prolactin-suppressive properties than dopamine itself.

Naturally just crushing up a bunch of Chasteberry is not likely to do the job, but proper preparation of the de-feminizing herb has finally given us an effective synergist to support male optimization.

So, cool, now that we have dealt with the HPTA suppression and feminizing issues. By doing so the obvious result is a notable and welcomed increase in testosterone production. But hey, why not push all the way and reach for optimization?

Increased Free Testosterone

Free-T (Proprietary Pure Avenacosides Matrix)
Seems most males who use supplements for either lean mass gains, libido augmentation or both have heard of Avena Sativa. Yeah, I know, lots of products already have some form avena sativa or its extracts in it, so what makes this one special? Of course we used an extraction process for maximum active compound content (greatest possible amount of active milligrams per capsule), but in truth Restore as a product is special, our Free-T (Proprietary Pure Avenacosides Matrix) from avena sativa just works well in the whole matrix to provide maximum results.

In the body testosterone travels around in two forms: Bound or inactive meaning it is bound to a protein called SHBGB, and Unbound or free meaning it is free to do manly things like build muscle and increase your capacity to perform sexually.

Basically there are phytochemicals in avena sativa called avenacosides A and B. Some studies indicate avenacosides increase actual active or free testosterone in the body by freeing up the bound testosterone from SHBG so there is more active testosterone. What good is it to have all kinds of extra testosterone if it is playing S & M games with SHBG?

Cortisol Inhibition

MbAET
Unless you went coma bound in the early 90�s you have been aware of the on going benefits reaped and progress made with DHEA and its even better metabolites. As an example are the patented and effective products 7-OXO-DHEA and of course 7-Hydroxy-DHEA analogs. Since these analogs prevent conversion into androgenic metabolites they have been touted by many as the best thing since pizza. Considering the lack of androgenic side effects possible while promoting fat loss, lean mass retention and even maximizing thyroid gland activity, not a real surprise they have become very popular. Of course oral bioavalability is pretty poor with most of these analogs thus requiring higher dosages.

Likely the most powerful and effective DHEA analog is b-AET (beta-androstenetriol). It has been shown in studies to be between 100 and 100,000 times more active than its DHEA precursor metabolites. However, like most DHEA analogs there is the issue of poor oral bioavailability. By supporting the delivery value through simple alkylation, MbAET is nearly 100% orally bioavailable and only takes a few milligrams to do its job.

Yeah. I know, get to the fat loss and lean muscle side of things in regard to MbAET

Glucocorticoids in humans are in two forms. Inactive cortisone and very active in eating muscle cortisol. There are two enzymes that are able to make each of these convert into the other.

11b-HSD-1: Converts inactive cortisone into cannibalistic cortisol. Studies have implicated this event in fat tissue as a pathway for increased fat storage. Part of the reason GH has a positive affect upon body composition is through its ability to inhibit 11b-HDS-1.

11b-HSD-2: Converts nasty cortisol into cortisone. 11betaHSD2 debulks intracellular cortisol by 90%. (Let the 11b-HSD-2 rule the house)

Hmmm, so, more 11b-HSD-1 means more cortisol which eats more muscle that likes to help fat do ugly things.

And less 11b-HSD-1 means

MbAET inhibits the 11b-HSD-1 enzyme both locally and systemically. This means that there is less conversion of cortisone to cortisol. Based upon the studies it appears that in mediating this pathway, it increases immune function and recovery of cells as well. Less cortisol and fat, more lean muscle and positive support to health. Not bad!

Optimized Delivery

CYP-X Proprietary Grapefruit Extract)

There were several studies some years back that showed a dramatic increase in absorption for some compounds when taken with grapefruit juice. The reason was due to a specific part of grapefruit called dihydoxybergamottin (DHB). It decreases the gastronomical destruction of compounds susceptible to the CYP-450 enzyme thus allowing a far greater amount of the compound to pass into the body's circulatory system instead of the toilet. The components of Restore are a good example

By creating an ultra pure active extract of dihydoxybergamottin (DHB) called CYP-X we have maximally increased the overall oral bioavailability of our synergistic compounds in Restore to allow both results and cost effective value in one product.

Don't Settle

Having anything less than optimal testosterone levels is unacceptable for any male wanting to be the best they can be in all things male, but as a man excess estrogen and cortisol is a bitch. Restore from ALR Industries is the newest complete synergistic weapon in the fight against mediocrity for all men.

Restore

Suggested Retail Price $70.99

Restore is a great product for anyone wanting to be an optimized male. Restore also stacks extremely well with Jungle Warfare

Research References:

1) Environment, human reproduction, menopause, and andropause.
Environ Health Perspect. 1993 Jul;101 Suppl 2:91-100. Review.

2) Acute exposure of adult male rats to dietary phytoestrogens reduces fecundity and alters epididymal steroid hormone receptor expression.
J Endocrinol. 2006 Jun;189(3):565-73.

3) [Phytoestrogens and soy foods in infants and children: caution is needed]
Arch Pediatr. 2006 Mar;13(3):235-7. Epub 2006 Feb 3.

4) Genistein, a phytoestrogen, effectively modulates luteinizing hormone and prolactin secretion in ovariectomized ewes during seasonal anestrus.
Neuroendocrinology. 2004 Feb;79(2):73-81.

5) Antiestrogens are partial estrogen agonists for prolactin production in primary pituitary cultures.
Mol Cell Endocrinol. 1986 Dec;48(2-3):127-33.

6) Stereochemistry of the functional group determines the mechanism of aromatase inhibition by 6-bromoandrostenedione.
Endocrinology. 1987 Sep;121(3):1010-6.

7) Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications.

8) Phytomedicine. 2003 May;10(4):348-57. Review.Immunopharmacol Immunotoxicol. 2005;27(1):15-32. Molecular specificity of 5-androstenediol as a systemic radioprotectant in mice. Whitnall MH, Villa V, Seed TM, Benjack J, Miner V, Lewbart ML, Dowding CA, Jackson WE 3rd.

9) J Clin Endocrinol Metab. 2005 Apr;90(4):2015-21. Epub 2005 Jan 25. Urinary markers of adrenarche: reference values in healthy subjects, aged 3-18 years. Remer T, Boye KR, Hartmann MF, Wudy SA. Department of Nutrition and Health, Research Institute of Child Nutrition, Heinstuck 11, 44225 Dortmund, Germany. remer@fke-do.de

10) Rinsho Byori. 1998 Jun;46(6):505-17. Control of the immune response by DHEA and its metabolites. Loria RM, Padgett DA. Department of Microbiology, Virginia Commonwealth University, Medical College of Virginia, Richmond 23298-09678, USA.

11) Ann N Y Acad Sci. 2000;917:860-7. Androstenetriol and androstenediol. Protection against lethal radiation and restoration of immunity after radiation injury. Loria RM, Conrad DH, Huff T, Carter H, Ben-Nathan D.

12) J Endocrinol. 2000 Feb;164(2):161-9. Conversion of dehydroepiandrosterone to downstream steroid hormones in macrophages. Schmidt M, Kreutz M, Loffler G, Scholmerich J, Straub RH. Institute of Biochemistry, Genetics and Microbiology, University of Regensburg, Germany.

13) J Neuroimmunol. 1998 Apr 1;84(1):61-8. Endocrine regulation of murine macrophage function: effects of dehydroepiandrosterone, androstenediol, and androstenetriol. Padgett DA, Loria RM. Department of Oral Biology, College of Dentistry, The Ohio State University, Columbus 43210, USA. padgett.11@osu.edu

14) Psychoneuroendocrinology. 1997;22 Suppl 1:S103-8. Antiglucocorticoid function of androstenetriol. Loria RM. Virginia Commonwealth University, Medical College of Virginia, Richmond 23298-0678, USA.Loria@gems.vcu.edu

15) Ann N Y Acad Sci. 1992 Apr 15;650:363-6. Mobilization of cutaneous immunity for systemic protection against infections. Loria RM, Padgett DA.
Virginia Commonwealth University, School of Basic Health Sciences, Medical College of Virginia, Richmond 23298.

16) Obes Res. 2005 Jul;13(7):1157-66. Increased cortisol bioavailability, abdominal obesity, and the metabolic syndrome in obese women. Duclos M, Marquez Pereira P, Barat P, Gatta B, Roger P

17) Laboratoire Neurogenetique et Stress, INSERM U471, Institut Francois Magendie, Universite Bordeaux II, rue C. Saint Saens, 33077 Bordeaux Cedex, France. duclos@pop.bordeaux.inserm.fr.

18) Horm Metab Res. 2005 Apr;37(4):193-7. Obesity and cortisol status. Salehi M, Ferenczi A, Zumoff B. Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel Medical Center and Albert Einstein College of Medicine, New York, NY 10003, USA.

19) Int J Parasitol.2004 Nov;34(12):1405-12. Effect of artemether alone and in combination with grapefruit juice on hepatic drug-metabolising enzymes and biochemical aspects in experimental Schistosoma mansoni.

20) Inhibition of in-vitro simvastatin metabolism in rat liver microsomes by bergamottin, a component of grapefruit juice. J Pharm Pharmacol. 2004 Aug;56(8):1007-14.

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 21 YEARS. DO NOT USE IF PREGNANT OR NURSING. KEEP OUT OF REACH OF CHILDREN. Do NOT consume this product if you have a medical condition and/or taking any prescription medication. Do not exceed recommended serving. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, severe headache, or other similar symptoms.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, or prevent any disease.

 

PLEASE NOTE: Product image is representative of the product offered but may not have the exact attributes. Please read product description for the specific attributes of this product.

 

PLEASE NOTE: The information above is intended for reference only. While we attempt to keep our information accurate, we cannot guarantee it is an accurate representation of the latest formulation of the product. If you have any concerns, please visit the vendor's web site. The information above are the views of the product's manufacturer, not the views of Muscle 4 Life Nutrition LLC. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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